Junfei Zhao
Postdoc Research Fellow
Department of Systems Biology
Department of Biomedical Informatics
Columbia University College of Physicians & Surgeons
ICRC Building 8th Floor, Office 811
1130 St. Nicholas Ave ยท New York, NY 10032
Email : jz2835(at)cumc.columbia.edu
Educational Background
- PhD Major in Operational Research & Bioinformatics(PhD-direct student), Academy of Mathematics & System Sciences, CAS, 2009.9 - 2014.07
- Bachelor Major in Information and Computing Science, Changsha University of science & technology, 2005.09 - 2009.06
Research Areas and Interests
Bioinformatics; System Biology.
Publications
- Zhao J, Cheng F, Zhao Z.
Tissue-specific signaling networks rewired by major somatic mutations in human cancer revealed by proteome-wide discovery.
Cancer Research (2017). doi: 10.1158/0008-5472.CAN-16-2460.
- Pora Kim, Junfei Zhao, Pinyi Lu, and Zhongming Zhao .
mutLBSgeneDB: mutated Ligand Binding Site gene DataBase.
Nucleic Acids Research (2017) 45 (D1): D256-D263.
- Peilin Jia, Guangchun Han, Junfei Zhao, Pinyi Lu, and Zhongming Zhao.
SZGR 2.0: a one-stop shop of schizophrenia candidate genes.
Nucleic Acids Research (2017) 45 (D1): D915-D924.
- Feixiong Cheng, Junfei Zhao (co-first author), Ariella B. Hanker, Monica Red Brewer, Carlos L. Arteaga, Zhongming Zhao.
Transcriptome and proteome-oriented identification of dysregulated eIF4G, STAT3, and Hippo pathways altered by PIK3CAH1047R in HER2/ER-positive breast cancer.
Breast Cancer Res Treat. 2016 Dec;160(3):457-474.
- Cheng, Feixiong, Junfei Zhao, Michaela Fooksa, and Zhongming Zhao .
A network-based drug repositioning infrastructure for precision cancer medicine through targeting significantly mutated genes in the human cancer genomes.
J Am Med Inform Assoc. 2016 Jul;23(4):681-91.
- Pora Kim, Feixiong Cheng, Junfei Zhao (co-first author), and Zhongming Zhao.
ccmGDB: a database for cancer cell metabolism genes.
Nucleic acids research 44.D1 (2016): D959-D968.
- Zhao J, Cheng F, Wang Y, Arteaga CL, Zhao Z.
Systematic prioritization of druggable mutations in ~5,000 genomes across 16 cancer types using a structural genomics-based approach.
Molecular & Cellular Proteomics (2015): mcp-M115.
- Cheng F, Zhao J, Zhao Z.
Advances in computational approaches for prioritizing driver mutations and significantly mutated genes in cancer genomes.
Brief Bioinform (2015) doi: 10.1093/bib/bbv068.
- Feixiong Cheng, Chuang Liu, Chen-Ching Lin, Junfei Zhao, Peilin Jia, Wen-Hsiung Li, Zhongming Zhao.
A Gene Gravity Model for the Evolution of Cancer Genomes: A Study of 3,000 Cancer Genomes across 9 Cancer Types.
PLOS Computational Biology (2015). DOI: 10.1371/journal.pcbi.1004497.
- Zhao M, Kim P, Mitra R, Zhao J, Zhao Z.
TSGene 2.0: an updated literature-based knowledgebase for tumor suppressor genes.
Nucleic acids research (2015): gkv1268.
- Junfei Zhao,Xiang-Sun Zhang, Shihua Zhang.
Predicting cooperative drug effects by the quantitative cellular profiling of response to individual drugs.
CPT Pharmacometrics Syst. Pharmacol (2014) 3, e1; doi:10.1038/psp.2013.79.
- James C Costello et al. (Junfei Zhao is listed as one co-author).
The challenge of drug sensitivity prediction: an assessment of methods through collaborative competition.
Nature Biotechnology (2014), doi: 10.1038/nbt.2877..
- Mukesh Bansal et al. (Junfei Zhao is listed as one co-author).
A community computational challenge to predict the activity of pairs of compounds.
Nature biotechnology 32.12 (2014): 1213-1222.
- Junfei Zhao, Shihua Zhang, Ling-Yun Wu, and Xiang-Sun Zhang.
Efficient methods for identifying mutated driver pathways in cancer.
Bioinformatics, doi: 10.1093/bioinformatics/bts564, 2012.
- Shihua Zhang, Junfei Zhao, Xiang-Sun Zhang.
Common community structure in time-varying networks.
Physical Review E, 85, 056110, 2012.
- Chen Chen, Junfei Zhao, Qiang Huang, Rui-Sheng Wang, Xiang-Sun Zhang.
Inferring domain-domain interactions from protein-protein interactions in the complex network conformation.
BMC Systems Biology (2012), 6(Suppl 1):S7.
- Junfei Zhao, Jiguang Wang, Xiang-Sun Zhang.
A SVC-based Method to Detect Multi-scalar Noisy Communities in Complex Networks.
ISORA 2011, pp. 133-143.
- Junhua Zhang, Shihua Zhang, Yong Wang, Junfei Zhao, Xiang-Sun Zhang.
Identifying Mutated Core Modules in Glioblastoma by Integrative Network Analysis.
2012 IEEE International Conference on Systems Biology (ISB), pp. 304-309.
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