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====== Junfei Zhao======

Postdoc Research Fellow
Department of Systems Biology
Department of Biomedical Informatics
Columbia University College of Physicians & Surgeons

ICRC Building 8th Floor, Office 811
1130 St. Nicholas Ave ยท New York, NY 10032
Email : [[jz2835(at)]]


=== {{color c="blue" text=" Educational Background "}} ===

~- PhD Major in Operational Research & Bioinformatics(PhD-direct student), Academy of Mathematics & System Sciences, CAS, 2009.9 - 2014.07

~- Bachelor Major in Information and Computing Science, Changsha University of science & technology, 2005.09 - 2009.06


=== {{color c="blue" text="Research Areas and Interests"}} ===

Bioinformatics; System Biology.

=== {{color c="blue" text="Publications"}} ===
~1) **Zhao J**, Cheng F, Zhao Z. ---**[[ Tissue-specific signaling networks rewired by major somatic mutations in human cancer revealed by proteome-wide discovery.]]**--- Cancer Research (2017). doi: 10.1158/0008-5472.CAN-16-2460.
~1) Pora Kim, **Junfei Zhao**, Pinyi Lu, and Zhongming Zhao . ---**[[ mutLBSgeneDB: mutated Ligand Binding Site gene DataBase.]]**--- Nucleic Acids Research (2017) 45 (D1): D256-D263.
~1) Peilin Jia, Guangchun Han, **Junfei Zhao**, Pinyi Lu, and Zhongming Zhao. ---**[[ SZGR 2.0: a one-stop shop of schizophrenia candidate genes.]]**--- Nucleic Acids Research (2017) 45 (D1): D915-D924.
~1) Feixiong Cheng, **Junfei Zhao** (co-first author), Ariella B. Hanker, Monica Red Brewer, Carlos L. Arteaga, Zhongming Zhao. ---**[[ Transcriptome and proteome-oriented identification of dysregulated eIF4G, STAT3, and Hippo pathways altered by PIK3CAH1047R in HER2/ER-positive breast cancer.]]**--- Breast Cancer Res Treat. 2016 Dec;160(3):457-474.
~1) Cheng, Feixiong, **Junfei Zhao**, Michaela Fooksa, and Zhongming Zhao . ---**[[ A network-based drug repositioning infrastructure for precision cancer medicine through targeting significantly mutated genes in the human cancer genomes.]]**--- J Am Med Inform Assoc. 2016 Jul;23(4):681-91.
~1) Pora Kim, Feixiong Cheng, **Junfei Zhao** (co-first author), and Zhongming Zhao. ---**[[ ccmGDB: a database for cancer cell metabolism genes.]]**--- Nucleic acids research 44.D1 (2016): D959-D968.
~1) **Zhao J**, Cheng F, Wang Y, Arteaga CL, Zhao Z. ---**[[ Systematic prioritization of druggable mutations in ~5,000 genomes across 16 cancer types using a structural genomics-based approach.]]**--- Molecular & Cellular Proteomics (2015): mcp-M115.
~1) Cheng F, **Zhao J**, Zhao Z. ---**[[ Advances in computational approaches for prioritizing driver mutations and significantly mutated genes in cancer genomes.]]**--- Brief Bioinform (2015) doi: 10.1093/bib/bbv068.
~1) Feixiong Cheng, Chuang Liu, Chen-Ching Lin, **Junfei Zhao**, Peilin Jia, Wen-Hsiung Li, Zhongming Zhao. ---**[[ A Gene Gravity Model for the Evolution of Cancer Genomes: A Study of 3,000 Cancer Genomes across 9 Cancer Types.]]**--- PLOS Computational Biology (2015). DOI: 10.1371/journal.pcbi.1004497.
~1) Zhao M, Kim P, Mitra R, **Zhao J**, Zhao Z. ---**[[ TSGene 2.0: an updated literature-based knowledgebase for tumor suppressor genes.]]**--- Nucleic acids research (2015): gkv1268.
~1) **Junfei Zhao**,Xiang-Sun Zhang, Shihua Zhang.---**[[ Predicting cooperative drug effects by the quantitative cellular profiling of response to individual drugs.]] **---CPT Pharmacometrics Syst. Pharmacol (2014) 3, e1; doi:10.1038/psp.2013.79.
~1) James C Costello et al. (**Junfei Zhao** is listed as one co-author).---**[[ The challenge of drug sensitivity prediction: an assessment of methods through collaborative competition.]] **---Nature Biotechnology (2014), doi: 10.1038/nbt.2877..
~1) Mukesh Bansal et al. (**Junfei Zhao** is listed as one co-author).---**[[ A community computational challenge to predict the activity of pairs of compounds.]] **---Nature biotechnology 32.12 (2014): 1213-1222.
~1) **Junfei Zhao**, Shihua Zhang, Ling-Yun Wu, and Xiang-Sun Zhang.---**[[ Efficient methods for identifying mutated driver pathways in cancer.]] **---//Bioinformatics//, doi: 10.1093/bioinformatics/bts564, 2012.
~1) Shihua Zhang, **Junfei Zhao**, Xiang-Sun Zhang.---**[[ Common community structure in time-varying networks.]] **---//Physical Review E//, 85, 056110, 2012.
~1) Chen Chen, **Junfei Zhao**, Qiang Huang, Rui-Sheng Wang, Xiang-Sun Zhang.---**[[ Inferring domain-domain interactions from protein-protein interactions in the complex network conformation]].**---BMC Systems Biology (2012), 6(Suppl 1):S7.
~1) **Junfei Zhao**, Jiguang Wang, Xiang-Sun Zhang.---**[[ A SVC-based Method to Detect Multi-scalar Noisy Communities in Complex Networks.]] **---ISORA 2011, pp. 133-143.
~1) Junhua Zhang, Shihua Zhang, Yong Wang, **Junfei Zhao**, Xiang-Sun Zhang. ---**[[ Identifying Mutated Core Modules in Glioblastoma by Integrative Network Analysis.]]**--- 2012 IEEE International Conference on Systems Biology (ISB), pp. 304-309.


=== {{color c="blue" text="Links"}} ===
~- [[ Nature]]
~- [[ PLoS]]
~- [[ Science]]
~- [[ PNAS]]
~- [[ CTEX]]
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