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Jiguangwang2 ==中文==

Jiguang Wang in Chengdu

Dr. Jiguang Wang (王吉光)

Postdoctoral Research Scientist

Department of Biomedical Informatics
Center for Computational Biology and Bioinformatics
Columbia University College of Physicians and Surgeons

1130 St. Nicholas Ave
ICRC Bldg 8th Floor, Office 804 D
New York, NY 10032

Jiguang Wang was born in Cangxian Hebei, China. He got his Ph.D. degree from AMSS of CAS in July 2011, and now is working in Columbia University College of Physicians and Surgeons as a Postdoctoral Research Scientist.

Education and Affiliation

Columbia logo
Postdoctoral Research Scientist (2011.10-now)
Columbia University

MU logo
Visiting Scholar (2011.7-2011.9)
University of Missouri

SIBS logo
Visiting Student (2009.11-2009.12; 2010.3-2010.4; 2010.5-2010.6; 2010.11-2010.12; 2011.5-2011.6)
Shanghai Institutes for Biological Sciences, CAS,

AMSS logo
Ph.D. student in Operations Research and Bioinformatics (2006.9-2011.7)
Academy of Mathematics & Systems Science, CAS

BIT logo
B.S. student in mathematics (2002.9-2006.7)
Beijing Institute of Technology


Research Interests

Research Project

Awards and Honors

Selected Publications

srep logo
Antisense non-coding RNA transcription targets AID to divergently transcribed genes in the B cell genome
Evangelos Pefanis*, Jiguang Wang*, Gerson Rothschild*, Junghyun Lim, Jaime Chao, Raul Rabadan, Aris N. Economides, Uttiya Basu
Nature, accepted (* co-first authors). New!

srep logo
The research on molecular network models of complex disease (in Chinese)
Sci Sin Math, 44(4): 317-328, doi: 10.1360/012013-143, 2014. New!

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Clinical impact of small TP53 mutated subclones in chronic lymphocytic leukemia
D Rossi, H Khiabanian, V Spina, C Ciardullo, A Bruscaggin, R Famà, Silvia Rasi, Sara Monti, Clara Deambrogi, Lorenzo De Paoli, Jiguang Wang, Valter Gattei, Anna Guarini, Robin Foà, Raul Rabadan, and Gianluca Gaidano
Blood, blood-2013-11-539726, 2014. New!

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PU. 1 is essential for MLL leukemia partially via crosstalk with the MEIS/HOX pathway
J Zhou, J Wu1, B Li1, D Liu, J Yu, X Yan, S Zheng, J Wang, L Zhang, L Zhang, F He, Q Li, A Chen, Y Zhang, X Zhao, Y Guan, X Zhao, J Yan1, J Ni, M A Nobrega, B Löwenberg, R Delwel, P J M Valk, A Kumar, L Xie, D G Tenen, G Huang and Q-f Wang
Leukemia, doi: 10.1038/leu.2013.384, 2014. New!

srep logo
Genetic lesions associated with chronic lymphocytic leukemia transformation to Richter syndrome.
Giulia Fabbri, Hossein Khiabanian, Antony B Holmes, Jiguang Wang, Monica Messina, Charles G Mullighan, Laura Pasqualucci, Raul Rabadan, Riccardo Dalla-Favera
Journal of Experimental Medicine, 10/2013; DOI:10.1084/jem.20131448, 2013.

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E3-ubiquitin ligase Nedd4 determines the fate of AID-associated RNA polymerase II in B cells.
Jianbo Sun, Celia D. Keim, Jiguang Wang, David Kazadi, Paula M. Oliver, Raul Rabadan and Uttiya Basu
Genes & Dev., 27: 1821-1833, 2013.

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B cell development and IL-10 secretion.
Uttiya Basu, Jianbo Sun, and Jiguang Wang
The Journal of Immunology, 190, 174.23, 2013.

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NOA: A Cytoscape Plugin for Network Ontology Analysis.
Chao Zhang*, Jiguang Wang*, Kristina Hanspers, Dong Xu, Luonan Chen, Alexander R. Pico.
Bioinformatics, 29 (16): 2066-2067, 2013. (* co-first authors)

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APG: an Active Protein-Gene Network Model to Quantify Regulatory Signals in Complex Biological Systems.
Jiguang Wang, Yidan Sun, Si Zheng, Xiang-Sun Zhang, Hua-Rong Zhou, Luonan Chen.
Scientific Reports, 3 : 1097, DOI: 10.1038/srep01097, 2013.

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Rewiring drug-activated p53-regulatory network from suppressing to promoting tumorigenesis.
Wei Song*, Jiguang Wang*, Ying Yang, Nai-He Jing, Xiang-Sun Zhang, Luonan Chen, Jia-Rui Wu
Journal of Molecular Cell Biology 4(3), doi: 10.1093/jmcb/mjs029, 2012 (* co-first authors).

Cancer Letters logo
Whole-exome Sequencing Reveals Recurrent Somatic Mutation Networks in Cancer.
Xiaoping Liu*, Jiguang Wang*, Luonan Chen.
Cancer Letters, 2012 (* co-first authors).

JEM logo
The coding genome of splenic marginal zone lymphoma: activation of NOTCH2 and other pathways regulating marginal zone development.
Davide Rossi, Vladimir Trifonov, Marco Fangazio, Alessio Bruscaggin, Silvia Rasi, Valeria Spina, Sara Monti, Tiziana Vaisitti, Francesca Arruga, Rosella Famà, Carmela Ciardullo, Mariangela Greco, Stefania Cresta, Daniela Piranda, Antony Holmes, Giulia Fabbri, Monica Messina, Andrea Rinaldi, Jiguang Wang, Claudio Agostinelli, Pier Paolo Piccaluga, Marco Lucioni, Fabrizio Tabbò, Roberto Serra, Silvia Franceschetti, Clara Deambrogi, Giulia Daniele, Valter Gattei, Roberto Marasca, Fabio Facchetti, Luca Arcaini, Giorgio Inghirami, Francesco Bertoni, Stefano A Pileri, Silvia Deaglio, Robin Foà, Riccardo Dalla-Favera, Laura Pasqualucci, Raul Rabadan, Gianluca Gaidano.
The Journal of Experimental Medicine , 209(9): 1537-1551, 2012.

NAR logo
NOA: a novel Network Ontology Analysis method.
Jiguang Wang, Qiang Huang, Zhi-Ping Liu, Yong Wang, Ling-Yun Wu, Luonan Chen, Xiang-Sun Zhang.
Nucleic Acids Research, doi: 10.1093/nar/gkr251, 2011.

PCB logo
Disease-aging network reveals significant roles of aging genes in connecting genetic diseases.
Jiguang Wang, Shihua Zhang, Yong Wang, Luonan Chen, and Xiang-Sun Zhang.
PLoS Comput Biol, 5(9): e1000521. doi:10.1371/journal.pcbi.1000521, 2009.

EPL logo
Modularity optimization in community detection of complex networks.
Xiang-Sun Zhang, Rui-Sheng Wang, Yong Wang, Jiguang Wang, Yu-Qing Qiu, Lin Wang, and Luonan Chen.
Europhysics Letters, 87: 38002, 2009.

JSSC logo
Remarks on network community properties
Jiguang Wang, Yuqing Qiu, Rui-Sheng Wang, Xiang-Sun Zhang.
Jrl Syst Sci & Complexity, 21: 637-644, 2008.

:::All publications and citations:::




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