Wiki source for JiguangWang
====== Prof. Jiguang Wang ======
""<img src="images/users/wjg3.JPG" alt="Jiguang Wang in Chengdu" style="float: right; margin: 0.0%; padding: 0.0%;">""
[[http://wang-lab.ust.hk/ Assistant Professor]] | [[http://wang-lab.ust.hk/ Lab Page at HKUST]] | [[http://zhangroup.aporc.org/Jiguangwang2 中文网页]] | Email: jgwang-at-ust.hk
Hong Kong University of Science and Technology, Clear Water Bay, Hong Kong
Jiguang Wang was born in Cangxian Hebei, China. He got his Ph.D. degree from AMSS of CAS in July 2011, and now is working at Hong Kong University of Sciecne and Technology as an Assistant Professor.
** {{image alt="New!" title="New!" url="images/new.gif"}} ** [[http://wang-lab.ust.hk/Opening.html Opening positions in Hong Kong University of Science and Technology.]]
=== {{color c="green" text=" Experience"}} ===
{{image class="left" alt="HKUST logo" url="images/users/wjg_HKUST.png" link="https://www.ust.hk/"}}
~- **2016-now** Assistant Professor, Hong Kong University of Science and Technology
{{image class="left" alt="Columbia logo" url="images/users/wjg_6.png" link="http://www.columbia.edu/"}}
~- **2015-2016** Associate Research Scientist, Columbia University
{{image class="left" alt="MU logo" url="images/users/wjg7.png" link="http://www.missouri.edu/"}}
~- **2011-2011** Visiting Scholar, University of Missouri
{{image class="left" alt="BIG logo" url="images/users/wjg_big.png" link="http://english.big.cas.cn/"}}
~- **2011-2013** Research Assistant Professor, Beijing Institute of Genomics
=== {{color c="green" text=" Training and Education"}} ===
{{image class="left" alt="Columbia logo" url="images/users/wjg_6.png" link="http://www.columbia.edu/"}}
~- **2011-2015** Postdoctoral Research Scientist, Columbia University
{{image class="left" alt="AMSS logo" url="images/users/wjg9.png" link="http://english.amss.cas.cn/"}}
~- **2006-2011** PhD in Applied Mathematics, AMSS, CAS
{{image class="left" alt="SIBS logo" url="images/users/wjg8.png" link="http://english.sibs.cas.cn/"}}
~- **2006-2011** Visiting Students, Shanghai Institute for Biological Sciences
{{image class="left" alt="BIT logo" url="images/users/wjg10.png" link="http://english.bit.edu.cn/"}}
~- **2002-2006** ScB in Applied Mathematics, Beijing Institute of Technology
------
{{image class="right" alt="Exotome" url="images/users/WJG5.png" link="https://rabadan.c2b2.columbia.edu/cgi-bin/hgGateway"}}
=== {{color c="green" text="Research Interests"}} ===
~- Precision Medicine
~- Cancer Genomics and Next Generation Sequencing
~- Transcriptome Assembly and Non-coding RNAs
~- Network Biology and Systems Biology
~- Operations Reseach
~- Machine Learning
=== {{color c="green" text="Research Projects"}} ===
~- **2015-** Topology of Cancer Evolution and Heterogeneity, Co-Investigator, NCI-U54
~- **2014-2018** Provocative Questions: Reconstruction of Evolutionary Networks using Cross-Sectional Genomic Data, Co-Investigator, NCI-R01
~- **2009-2010** The research of dynamic model and algorithms for network biomarkers in type 2 diabetes, Principal Investigator, Ph. D research project supported by Chinese Academy of Sciences
=== {{color c="green" text="Awards and Honors"}} ===
~- **2016** [[http://www.sacbmeeting.org/ Travel Fellowship of SYSTEMS APPROACHES TO CANCER BIOLOGY (SACB meeting)]]
~- **2015** [[http://irvinginstitute.columbia.edu/resources/pmed_fellow_ship.html Precision Medicine Fellowship, Irving Institute for Clinical and Translational Research]]
~- **2014** Travel Fellowship of 10th International Symposium on Bioinformatics Research and Applications
~- **2012** [[http://news.sciencenet.cn/htmlnews/2012/11/271425.shtm Excellent PhD thesis Award of Chinese Academy of Science]]
~- **2011** [[http://www.gucas.ac.cn/site/157?u=59493 Special Prize of President Scholarship for Postgraduate Students of Chinese Academy of Science]]
~- **2009** [[http://www.amt.ac.cn/education/prize.html The Presidential Outstanding Research Scholarship from AMSS, CAS]]
~- **2007** Merit Student in AMSS
~- **2006** Beijing Outstanding Graduates and Admission with waiver of postgraduate entrance examination
~- **2005** Honorable Prize in Mathematical Contest in Modeling and Second class Prize in CUMCM
~- **2004** Second class Prize in CUMCM
~- **2002** First class Prize in Chinese Mathematical Olympiad and Admission with waiver of national college admission examination
=== {{color c="green" text="Selected Publications"}} ===
[[http://scholar.google.com/citations?hl=en&user=OIWfp-QAAAAJ Google Citation]] | [[http://www.researcherid.com/rid/B-2717-2012 ResearcherID:B-2717-2012]] | [[http://www.researchgate.net/profile/Jiguang_Wang2/ ResearchGate]]
{{image class="left" alt="srep logo" url="images/users/wjg_NG2016.png" link="http://www.nature.com/ng/journal/vaop/ncurrent/full/ng.3590.html"}}
~~ Clonal Evolution of Glioblastoma under Therapy.
~~ **[[http://zhangroup.aporc.org/JiguangWang Jiguang Wang]]**, Emanuela Cazzato, Erik Ladewig, Veronique Frattini, Daniel I. S. Rosenbloom, Sakellarios Zairis, Francesco Abate, Zhaoqi Liu, Oliver Elliott, Yong-Jae Shin, Jin-Ku Lee, In-Hee Lee, Woong-Yang Park, Marica Eoli, Andrew Blumberg, Anna Lasorella, Do-Hyun Nam#, Gaetano Finocchiaro#, Antonio Iavarone#, Raul Rabadan#.
~~ //Nature Genetics//, 48, 768–776, 2016. --- ** {{image alt="New!" title="New!" url="images/new.gif"}} **
{{image class="left" alt="srep logo" url="images/users/wjg28_elife.png" link="http://elifesciences.org/content/3/e02869"}}
~~ [[https://elifesciences.org/content/5/e14709 Kinase-dead ATM protein is highly oncogenic and can be preferentially targeted by Topoisomerase I inhibitors.]]
~~ Kenta Yamamoto, **[[http://zhangroup.aporc.org/JiguangWang Jiguang Wang]]**, Lisa Sprinzen, Jun Xu, Christopher J. Haddock, Chen Li, Brian J. Lee, Denis G. Loredan, Wenxia Jiang, Alessandro Vindigni, Dong Wang, Raul Rabadan and Shan Zha.
~~//eLife//, 10.7554/eLife.14709, 2016.
{{image class="left" alt="srep logo" url="images/users/wjg_cell.png" link="http://www.cell.com/cell/abstract/S0092-8674(15)00490-0"}}
~~ RNA-Exosome-Regulated Long Non-coding RNA Transcription Controls Super-Enhancer Activity.
~~ Evangelos Pefanis*, **[[http://zhangroup.aporc.org/JiguangWang Jiguang Wang*]]**, Gerson Rothschild*, Junghyun Lim*, Kazadi D, Sun J, Federation A, Chao J, Elliott O, Liu ZP, Economides AN, Bradner JE, Rabadan R, Basu U.
~~ //Cell//, Volume 161, Issue 4, p774–789, 7 May 2015. (*First authors) [[http://rabadan.c2b2.columbia.edu/cgi-bin/hgGateway EXOTOME browser]]
{{image class="left" alt="srep logo" url="images/users/wjg28_elife.png" link="http://elifesciences.org/content/3/e02869"}}
~~ [[http://elifesciences.org/content/3/e02869 Tumor evolutionary directed graphs and the history of chronic lymphocytic leukemia]]
~~ **[[http://zhangroup.aporc.org/JiguangWang Jiguang Wang#]]**, Hossein Khiabanian, Davide Rossi, Giulia Fabbri, Valter Gattei, Francesco Forconi, Luca Laurenti, Roberto Marasca, Giovanni Del Poeta, Robin Foà, Laura Pasqualucci, Gianluca Gaidano, Raul Rabadan#.
~~//eLife//, DOI:10.7554/eLife.02869, 2014. (#corresponding authors). [[http://systemsbiology.columbia.edu/news/distinguishing-patterns-of-tumor-evolution-in-chronic-lymphocytic-leukemia :::News in Columbia:::]] ---
{{image class="left" alt="srep logo" url="images/users/wjg27.png" link="http://www.nature.com/nature/journal/vaop/ncurrent/full/nature13580.html"}}
~~ [[http://www.nature.com/nature/journal/vaop/ncurrent/full/nature13580.html Noncoding RNA transcription targets AID to divergently transcribed loci in B cells]]
~~ Evangelos Pefanis*, **[[http://zhangroup.aporc.org/JiguangWang Jiguang Wang*]]**, Gerson Rothschild*, Junghyun Lim, Jaime Chao, Raul Rabadan, Aris N. Economides, Uttiya Basu
~~ //Nature//, 514(7522), 389–393, doi:10.1038/nature13580, 2014. (* co-first authors). --- [[http://f1000.com/prime/718530138 :::This paper has been evaluated by F1000:::]]
{{image class="left" alt="srep logo" url="images/users/wjg_cell2016.png" link="http://www.sciencedirect.com/science/article/pii/S009286741501692X"}}
~~ Molecular Profiling Reveals Biologically Discrete Subsets and Pathways of Progression in Diffuse Glioma.
~~ Michele Ceccarelli, Floris P Barthel, Tathiane M Malta, Thais S Sabedot, Sofie R Salama, Bradley A Murray, Olena Morozova, Yulia Newton, Amie Radenbaugh, Stefano M Pagnotta, Samreen Anjum, **[[http://zhangroup.aporc.org/JiguangWang Jiguang Wang]]**, Ganiraju Manyam, Pietro Zoppoli, Shiyun Ling, Arjun A Rao, Mia Grifford, Andrew D Cherniack, Hailei Zhang, Laila Poisson, Carlos Gilberto Carlotti, Daniela Pretti da Cunha Tirapelli, Arvind Rao, Tom Mikkelsen, Ching C Lau, WK Alfred Yung, Raul Rabadan, Jason Huse, Daniel J Brat, Norman L Lehman, Jill S Barnholtz-Sloan, Siyuan Zheng, Kenneth Hess, Ganesh Rao, Matthew Meyerson, Rameen Beroukhim, Lee Cooper, Rehan Akbani, Margaret Wrensch, David Haussler, Kenneth D Aldape, Peter W Laird, David H Gutmann, TCGA Research Network, Houtan Noushmehr, Antonio Iavarone, Roel GW Verhaak.
~~ //Cell//, Volume 164, Issue 3, 550-563, 2016.
{{image class="left" alt="srep logo" url="images/users/cr2015.png" link="http://www.cell.com/cell-reports/fulltext/S2211-1247(15)01112-2"}}
~~ Transcriptomics identify CD9 as a marker of murine IL10-competent regulatory B cells.
~~ Jianbo Sun, **[[http://zhangroup.aporc.org/JiguangWang Jiguang Wang]]**, Evangelos Pefanis, Jaime Chao, Gerson Rothschild, Isao Tachibana, Jun Kui Chen, Ivaylo I. Ivanov, Raul Rabadan, Yoshito Takeda, Uttiya Basu
~~ //Cell Reports//, Volume 13, Issue 6, p1110–1117, 10 November 2015.
{{image class="left" alt="NAR logo" url="images/users/wjg15.png" link="http://nar.oxfordjournals.org/content/39/13/e87"}}
~~ NOA: a novel Network Ontology Analysis method.
~~ **[[http://zhangroup.aporc.org/JiguangWang Jiguang Wang]]**, Qiang Huang, Zhi-Ping Liu, Yong Wang, Ling-Yun Wu, Luonan Chen, Xiang-Sun Zhang.
~~ //Nucleic Acids Research//, doi: 10.1093/nar/gkr251, 2011.
~~ [[http://www.aporc.org/noa/ ::NOA Webserver::]] [[http://f1000.com/10865956 :::This paper has been evaluated by F1000:::]]
{{image class="left" alt="PCB logo" url="images/users/wjg16.png" link="http://www.ploscompbiol.org/article/info%3Adoi%2F10.1371%2Fjournal.pcbi.1000521"}}
~~ Disease-aging network reveals significant roles of aging genes in connecting genetic diseases.
~~ **[[http://zhangroup.aporc.org/JiguangWang Jiguang Wang]]**, Shihua Zhang, Yong Wang, Luonan Chen, and Xiang-Sun Zhang.
~~ //PLoS Comput Biol//, 5(9): e1000521. doi:10.1371/journal.pcbi.1000521, 2009.---
{{image class="left" alt="srep logo" url="images/users/ot2016.png" link="http://www.ncbi.nlm.nih.gov/pubmed/26883104"}}
~~ Prognostic and therapeutic role of targetable lesions in B-lineage acute lymphoblastic leukemia without recurrent fusion genes.
~~ M Messina*, S Chiaretti*, **[[http://zhangroup.aporc.org/JiguangWang Jiguang Wang*]]**, AL Fedullo, N Peragine, V Gianfelici, A Piciocchi, F Brugnoletti, F Di Giacomo, S Pauselli, AB Holmes, MC Puzzolo, G Ceglie, V Apicella, M Mancini, G Te Kronnie, AM Testi, A Vitale, M Vignetti, A Guarini, R Rabadan, R Foà.
~~ //Oncotarget//, doi: 10.18632/oncotarget.7356, 2016. --- [[http://f1000.com/prime/726151961 :::This paper has been evaluated by F1000:::]]
{{image class="left" alt="srep logo" url="images/users/wjg_mbs2016.png" link="http://pubs.rsc.org/is/content/articlelanding/2016/mb/c5mb00782h#!divAbstract"}}
~~ Network stratification analysis for identifying function-specific network layers.
~~ C Zhang*, **[[http://zhangroup.aporc.org/JiguangWang Jiguang Wang*]]**, C Zhang, J Liu, D Xu, L Chen.
~~ //Molecular BioSystems//, 12(4):1232-40, 2016.
{{image class="left" alt="srep logo" url="images/users/BJH2015.png" link="http://onlinelibrary.wiley.com/doi/10.1111/bjh.13859/full"}}
~~ [[http://onlinelibrary.wiley.com/doi/10.1111/bjh.13859/full Inter- and intra-patient clonal and subclonal heterogeneity of chronic lymphocytic leukaemia: evidences from circulating and lymph nodal compartments]]
~~ Ilaria Del Giudice*, Marilisa Marinelli*, **[[http://zhangroup.aporc.org/JiguangWang Jiguang Wang*]]**, Silvia Bonina, Monica Messina, Sabina Chiaretti, Caterina Ilari, Luciana Cafforio, Sara Raponi, Francesca R. Mauro, Valeria Di Maio, Maria S. De Propris, Mauro Nanni, Carmela Ciardullo, Davide Rossi, Gianluca Gaidano, Anna Guarini, Raul Rabadan and Robin Foà.
~~ //British Journal of Haematology//, DOI: 10.1111/bjh.13859, 2015. (* co-first authors).
{{image class="left" alt="srep logo" url="images/users/jmcb2015.png" link="http://jmcb.oxfordjournals.org/content/7/3/203"}}
~~ An information theoretic method to identify combinations of genomic alterations that promote glioblastoma.
~~ Rachel D. Melamed, **[[http://zhangroup.aporc.org/JiguangWang Jiguang Wang]]**, Antonio Iavarone and Raul Rabadan.
~~ //J Mol Cell Biol//, doi: 10.1093/jmcb/mjv026, 2015.
{{image class="left" alt="srep logo" url="images/users/wjg29cbio.png" link="http://benthamscience.com/journals/current-bioinformatics/article/138764/"}}
~~ Network propagation reveals novel genetic features predicting drug response of cancer cell lines.
~~ **[[http://zhangroup.aporc.org/JiguangWang Jiguang Wang*]]**, Judith Kribelbauer*, Raul Rabadan.
~~ //Current Bioinformatics//, Volume 11, issue 5, 2016.
{{image class="left" alt="srep logo" url="images/users/wjg26.png" link="http://math.scichina.com:8081/sciA/CN/abstract/abstract514035.shtml"}}
~~ The research on molecular network models of complex disease (in Chinese)
~~**[[http://zhangroup.aporc.org/JiguangWang Jiguang Wang*]]**
~~ //Sci Sin Math//, 44(4): 317-328, doi: 10.1360/012013-143, 2014.
{{image class="left" alt="srep logo" url="images/users/wjg23.png" link="http://bloodjournal.hematologylibrary.org/content/early/2014/02/05/blood-2013-11-539726.short"}}
~~ Clinical impact of small TP53 mutated subclones in chronic lymphocytic leukemia
~~ D Rossi, H Khiabanian, V Spina, C Ciardullo, A Bruscaggin, R Famà, Silvia Rasi, Sara Monti, Clara Deambrogi, Lorenzo De Paoli, **[[http://zhangroup.aporc.org/JiguangWang Jiguang Wang]]**, Valter Gattei, Anna Guarini, Robin Foà, Raul Rabadan, and Gianluca Gaidano
~~ //Blood//, blood-2013-11-539726, 2014.
{{image class="left" alt="srep logo" url="images/users/wjg22.png" link="http://www.nature.com/leu/journal/vaop/ncurrent/full/leu2013384a.html"}}
~~ PU. 1 is essential for MLL leukemia partially via crosstalk with the MEIS/HOX pathway
~~ J Zhou, J Wu, B Li, D Liu, J Yu, X Yan, S Zheng, **[[http://zhangroup.aporc.org/JiguangWang J Wang]]**, L Zhang, L Zhang, F He, Q Li, A Chen, Y Zhang, X Zhao, Y Guan, X Zhao, J Yan, J Ni, M A Nobrega, B Löwenberg, R Delwel, P J M Valk, A Kumar, L Xie, D G Tenen, G Huang and Q-f Wang
~~ //Leukemia//, doi: 10.1038/leu.2013.384, 2014.
{{image class="left" alt="srep logo" url="images/users/wjg21.png" link="http://jem.rupress.org/content/210/11/2273.abstract"}}
~~ Genetic lesions associated with chronic lymphocytic leukemia transformation to Richter syndrome.
~~ Giulia Fabbri, Hossein Khiabanian, Antony B Holmes, **[[http://zhangroup.aporc.org/JiguangWang Jiguang Wang]]**, Monica Messina, Charles G Mullighan, Laura Pasqualucci, Raul Rabadan, Riccardo Dalla-Favera
~~ //Journal of Experimental Medicine//, 10/2013; DOI:10.1084/jem.20131448, 2013.
{{image class="left" alt="srep logo" url="images/users/wjg20.png" link="http://genesdev.cshlp.org/content/27/16/1821.full"}}
~~ E3-ubiquitin ligase Nedd4 determines the fate of AID-associated RNA polymerase II in B cells.
~~ Jianbo Sun, Celia D. Keim, **[[http://zhangroup.aporc.org/JiguangWang Jiguang Wang]]**, David Kazadi, Paula M. Oliver, Raul Rabadan and Uttiya Basu
~~ //Genes & Dev.//, 27: 1821-1833, 2013.
{{image class="left" alt="srep logo" url="images/users/wjg24.png" link="http://www.jimmunol.org/cgi/content/meeting_abstract/190/1_MeetingAbstracts/174.23"}}
~~ B cell development and IL-10 secretion.
~~Uttiya Basu, Jianbo Sun, and **[[http://zhangroup.aporc.org/JiguangWang Jiguang Wang]]**
~~//The Journal of Immunology//, 190, 174.23, 2013.
{{image class="left" alt="srep logo" url="images/users/wjg19.gif" link="http://bioinformatics.oxfordjournals.org/content/early/2013/07/03/bioinformatics.btt334"}}
~~ NOA: A Cytoscape Plugin for Network Ontology Analysis.
~~ Chao Zhang*, **[[http://zhangroup.aporc.org/JiguangWang Jiguang Wang*]]**, Kristina Hanspers, Dong Xu, Luonan Chen, Alexander R. Pico.
~~ //Bioinformatics//, 29 (16): 2066-2067, 2013. (* co-first authors)
~~ [[http://apps.cytoscape.org/apps/noa NOA is now available in Cytoscape!! App store and Plug-in manager]]
{{image class="left" alt="srep logo" url="images/users/wjg11.png" link="http://www.nature.com/srep/2013/130121/srep01097/full/srep01097.html"}}
~~ APG: an Active Protein-Gene Network Model to Quantify Regulatory Signals in Complex Biological Systems.
~~ **[[http://zhangroup.aporc.org/JiguangWang Jiguang Wang]]**, Yidan Sun, Si Zheng, Xiang-Sun Zhang, Hua-Rong Zhou, Luonan Chen.
~~ //Scientific Reports//, 3 : 1097, DOI: 10.1038/srep01097, 2013.
{{image class="left" alt="JMCB logo" url="images/users/wjg14.png" link="http://jmcb.oxfordjournals.org/content/4/4/197"}}
~~ Rewiring drug-activated p53-regulatory network from suppressing to promoting tumorigenesis.
~~ Wei Song*, **[[http://zhangroup.aporc.org/JiguangWang Jiguang Wang*]]**, Ying Yang, Nai-He Jing, Xiang-Sun Zhang, Luonan Chen, Jia-Rui Wu
~~ //Journal of Molecular Cell Biology // 4(3), doi: 10.1093/jmcb/mjs029, 2012 (* co-first authors).
{{image class="left" alt="Cancer Letters logo" url="images/users/wjg12.png" link="http://www.sciencedirect.com/science/article/pii/S0304383512006490#"}}
~~ Whole-exome Sequencing Reveals Recurrent Somatic Mutation Networks in Cancer.
~~ Xiaoping Liu*, **[[http://zhangroup.aporc.org/JiguangWang Jiguang Wang*]]**, Luonan Chen.
~~ //Cancer Letters//, 2012 (* co-first authors).
{{image class="left" alt="JEM logo" url="images/users/wjg13.png" link="http://jem.rupress.org/content/early/2012/08/07/jem.20120904.short"}}
~~ The coding genome of splenic marginal zone lymphoma: activation of NOTCH2 and other pathways regulating marginal zone development.
~~ Davide Rossi, Vladimir Trifonov, Marco Fangazio, Alessio Bruscaggin, Silvia Rasi, Valeria Spina, Sara Monti, Tiziana Vaisitti, Francesca Arruga, Rosella Famà, Carmela Ciardullo, Mariangela Greco, Stefania Cresta, Daniela Piranda, Antony Holmes, Giulia Fabbri, Monica Messina, Andrea Rinaldi, **[[http://zhangroup.aporc.org/JiguangWang Jiguang Wang]]**, Claudio Agostinelli, Pier Paolo Piccaluga, Marco Lucioni, Fabrizio Tabbò, Roberto Serra, Silvia Franceschetti, Clara Deambrogi, Giulia Daniele, Valter Gattei, Roberto Marasca, Fabio Facchetti, Luca Arcaini, Giorgio Inghirami, Francesco Bertoni, Stefano A Pileri, Silvia Deaglio, Robin Foà, Riccardo Dalla-Favera, Laura Pasqualucci, Raul Rabadan, Gianluca Gaidano.
~~ //The Journal of Experimental Medicine //, 209(9): 1537-1551, 2012.
{{image class="left" alt="EPL logo" url="images/users/wjg17.png" link="http://www.iop.org/EJ/abstract/0295-5075/87/3/38002"}}
~~ Modularity optimization in community detection of complex networks.
~~ Xiang-Sun Zhang, Rui-Sheng Wang, Yong Wang, **[[http://zhangroup.aporc.org/JiguangWang Jiguang Wang]]**, Yu-Qing Qiu, Lin Wang, and Luonan Chen.
~~ // Europhysics Letters//, 87: 38002, 2009.
~~ [[http://zhangroup.aporc.org/images/files/epl.pdf ::PDF download::]] [[http://iopscience.iop.org/0295-5075/page/Best%20of%202009%20Collection :::This paper is selected as EPL Best of 2009 collection:::]]
{{image class="left" alt="JSSC logo" url="images/users/wjg18.png" link="http://www.springerlink.com/content/7241802320q57g74/?p=f9a87302648f43d3b9d7c0386b86459f&pi=10"}}
~~ Remarks on network community properties
~~ **[[http://zhangroup.aporc.org/JiguangWang Jiguang Wang]]**, Yuqing Qiu, Rui-Sheng Wang, Xiang-Sun Zhang.
~~ //Jrl Syst Sci & Complexity//, 21: 637-644, 2008.
~~ [[http://zhangroup.aporc.org/images/files/2008-J-10-jssc.pdf ::PDF download::]] ---
=== {{color c="green" text="Books"}} ===
~-PhD Thesis: The Research on Molecular Network Models of Complex Disease, [[http://zhangroup.aporc.org/jiguangwangPhdThesisAbstract Abstract]]
~-Contribution to [[http://www.springer.com/new+%26+forthcoming+titles+(default)/book/978-1-4419-9862-0 Encyclopedia of Systems Biology]]: Clustering methods, Co-expression, Edge ontology, Functional enrichment analysis, Gene ontology, Ontology analysis of biological networks, Partial correlation coefficient, Pearson correlation coefficient, Time-delay correlation
----
=== {{color c="green" text="Links"}} ===
~-[[https://rabadan.c2b2.columbia.edu/cgi-bin/hgGateway EXOTOME browser]] | [[http://nrnb.org/tools/noa NOA Manual Page in NRNB]] | [[http://apps.cytoscape.org/apps/noa NOA Cytoscape Plug-in in Cytoscape App Store]] | [[http://www.aporc.org/noa/ NOA Webserver]]
~-[[http://www.c2b2.columbia.edu/rabadan/ Rabadan Lab]] | [[http://www.basulabcolumbia.org Basu Lab]] | [[http://sourcedb.big.cas.cn/yw/pl/fs/201101/t20110127_3068704.html Wang Lab]] | [[http://digbio.missouri.edu/ Xu's Digital Biology Lab]] | [[http://www.sysbio.ac.cn/cb/chenlab/index.htm Chen Lab]] | [[http://zhangroup.aporc.org/ Zhangroup]]
~-[[http://www.iscb.org/ ISCB ]] | [[http://www.bioinformatics.fr/jobs.php Bioinformatics Jobs]]
~-[[http://www.columbia.edu/ Columbia University]] | [[http://www.missouri.edu/ University of Missouri]] | [[http://english.big.cas.cn/ Beijing Institute of Genomics]] | [[http://english.amss.cas.cn/ Academy of Mathematics & Systems Science]] | [[http://english.bit.edu.cn/ Beijing Institute of Technology]] | [[http://www.czez.cn/Index.html Cangzhou secondary high school]]
~- [[http://systemsbiology.columbia.edu/news/distinguishing-patterns-of-tumor-evolution-in-chronic-lymphocytic-leukemia Distinguishing Patterns of Tumor Evolution in Chronic Lymphocytic Leukemia]]
~- [[https://www.dbmi.columbia.edu/2015/04/congratulations-to-jiguang-wang/ Jiguang Wang named Irving Institute Precision Fellow]]
~- [[http://irvinginstitute.columbia.edu/resources/pmed_fellow_ship.html Irving Institute for Clinical and Translational research]]
~- [[http://wang-lab.ust.hk/ Wang Genomic Lab @HKUST]]
::c::----
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""<img src="images/users/wjg3.JPG" alt="Jiguang Wang in Chengdu" style="float: right; margin: 0.0%; padding: 0.0%;">""
[[http://wang-lab.ust.hk/ Assistant Professor]] | [[http://wang-lab.ust.hk/ Lab Page at HKUST]] | [[http://zhangroup.aporc.org/Jiguangwang2 中文网页]] | Email: jgwang-at-ust.hk
Hong Kong University of Science and Technology, Clear Water Bay, Hong Kong
Jiguang Wang was born in Cangxian Hebei, China. He got his Ph.D. degree from AMSS of CAS in July 2011, and now is working at Hong Kong University of Sciecne and Technology as an Assistant Professor.
** {{image alt="New!" title="New!" url="images/new.gif"}} ** [[http://wang-lab.ust.hk/Opening.html Opening positions in Hong Kong University of Science and Technology.]]
=== {{color c="green" text=" Experience"}} ===
{{image class="left" alt="HKUST logo" url="images/users/wjg_HKUST.png" link="https://www.ust.hk/"}}
~- **2016-now** Assistant Professor, Hong Kong University of Science and Technology
{{image class="left" alt="Columbia logo" url="images/users/wjg_6.png" link="http://www.columbia.edu/"}}
~- **2015-2016** Associate Research Scientist, Columbia University
{{image class="left" alt="MU logo" url="images/users/wjg7.png" link="http://www.missouri.edu/"}}
~- **2011-2011** Visiting Scholar, University of Missouri
{{image class="left" alt="BIG logo" url="images/users/wjg_big.png" link="http://english.big.cas.cn/"}}
~- **2011-2013** Research Assistant Professor, Beijing Institute of Genomics
=== {{color c="green" text=" Training and Education"}} ===
{{image class="left" alt="Columbia logo" url="images/users/wjg_6.png" link="http://www.columbia.edu/"}}
~- **2011-2015** Postdoctoral Research Scientist, Columbia University
{{image class="left" alt="AMSS logo" url="images/users/wjg9.png" link="http://english.amss.cas.cn/"}}
~- **2006-2011** PhD in Applied Mathematics, AMSS, CAS
{{image class="left" alt="SIBS logo" url="images/users/wjg8.png" link="http://english.sibs.cas.cn/"}}
~- **2006-2011** Visiting Students, Shanghai Institute for Biological Sciences
{{image class="left" alt="BIT logo" url="images/users/wjg10.png" link="http://english.bit.edu.cn/"}}
~- **2002-2006** ScB in Applied Mathematics, Beijing Institute of Technology
------
{{image class="right" alt="Exotome" url="images/users/WJG5.png" link="https://rabadan.c2b2.columbia.edu/cgi-bin/hgGateway"}}
=== {{color c="green" text="Research Interests"}} ===
~- Precision Medicine
~- Cancer Genomics and Next Generation Sequencing
~- Transcriptome Assembly and Non-coding RNAs
~- Network Biology and Systems Biology
~- Operations Reseach
~- Machine Learning
=== {{color c="green" text="Research Projects"}} ===
~- **2015-** Topology of Cancer Evolution and Heterogeneity, Co-Investigator, NCI-U54
~- **2014-2018** Provocative Questions: Reconstruction of Evolutionary Networks using Cross-Sectional Genomic Data, Co-Investigator, NCI-R01
~- **2009-2010** The research of dynamic model and algorithms for network biomarkers in type 2 diabetes, Principal Investigator, Ph. D research project supported by Chinese Academy of Sciences
=== {{color c="green" text="Awards and Honors"}} ===
~- **2016** [[http://www.sacbmeeting.org/ Travel Fellowship of SYSTEMS APPROACHES TO CANCER BIOLOGY (SACB meeting)]]
~- **2015** [[http://irvinginstitute.columbia.edu/resources/pmed_fellow_ship.html Precision Medicine Fellowship, Irving Institute for Clinical and Translational Research]]
~- **2014** Travel Fellowship of 10th International Symposium on Bioinformatics Research and Applications
~- **2012** [[http://news.sciencenet.cn/htmlnews/2012/11/271425.shtm Excellent PhD thesis Award of Chinese Academy of Science]]
~- **2011** [[http://www.gucas.ac.cn/site/157?u=59493 Special Prize of President Scholarship for Postgraduate Students of Chinese Academy of Science]]
~- **2009** [[http://www.amt.ac.cn/education/prize.html The Presidential Outstanding Research Scholarship from AMSS, CAS]]
~- **2007** Merit Student in AMSS
~- **2006** Beijing Outstanding Graduates and Admission with waiver of postgraduate entrance examination
~- **2005** Honorable Prize in Mathematical Contest in Modeling and Second class Prize in CUMCM
~- **2004** Second class Prize in CUMCM
~- **2002** First class Prize in Chinese Mathematical Olympiad and Admission with waiver of national college admission examination
=== {{color c="green" text="Selected Publications"}} ===
[[http://scholar.google.com/citations?hl=en&user=OIWfp-QAAAAJ Google Citation]] | [[http://www.researcherid.com/rid/B-2717-2012 ResearcherID:B-2717-2012]] | [[http://www.researchgate.net/profile/Jiguang_Wang2/ ResearchGate]]
{{image class="left" alt="srep logo" url="images/users/wjg_NG2016.png" link="http://www.nature.com/ng/journal/vaop/ncurrent/full/ng.3590.html"}}
~~ Clonal Evolution of Glioblastoma under Therapy.
~~ **[[http://zhangroup.aporc.org/JiguangWang Jiguang Wang]]**, Emanuela Cazzato, Erik Ladewig, Veronique Frattini, Daniel I. S. Rosenbloom, Sakellarios Zairis, Francesco Abate, Zhaoqi Liu, Oliver Elliott, Yong-Jae Shin, Jin-Ku Lee, In-Hee Lee, Woong-Yang Park, Marica Eoli, Andrew Blumberg, Anna Lasorella, Do-Hyun Nam#, Gaetano Finocchiaro#, Antonio Iavarone#, Raul Rabadan#.
~~ //Nature Genetics//, 48, 768–776, 2016. --- ** {{image alt="New!" title="New!" url="images/new.gif"}} **
{{image class="left" alt="srep logo" url="images/users/wjg28_elife.png" link="http://elifesciences.org/content/3/e02869"}}
~~ [[https://elifesciences.org/content/5/e14709 Kinase-dead ATM protein is highly oncogenic and can be preferentially targeted by Topoisomerase I inhibitors.]]
~~ Kenta Yamamoto, **[[http://zhangroup.aporc.org/JiguangWang Jiguang Wang]]**, Lisa Sprinzen, Jun Xu, Christopher J. Haddock, Chen Li, Brian J. Lee, Denis G. Loredan, Wenxia Jiang, Alessandro Vindigni, Dong Wang, Raul Rabadan and Shan Zha.
~~//eLife//, 10.7554/eLife.14709, 2016.
{{image class="left" alt="srep logo" url="images/users/wjg_cell.png" link="http://www.cell.com/cell/abstract/S0092-8674(15)00490-0"}}
~~ RNA-Exosome-Regulated Long Non-coding RNA Transcription Controls Super-Enhancer Activity.
~~ Evangelos Pefanis*, **[[http://zhangroup.aporc.org/JiguangWang Jiguang Wang*]]**, Gerson Rothschild*, Junghyun Lim*, Kazadi D, Sun J, Federation A, Chao J, Elliott O, Liu ZP, Economides AN, Bradner JE, Rabadan R, Basu U.
~~ //Cell//, Volume 161, Issue 4, p774–789, 7 May 2015. (*First authors) [[http://rabadan.c2b2.columbia.edu/cgi-bin/hgGateway EXOTOME browser]]
{{image class="left" alt="srep logo" url="images/users/wjg28_elife.png" link="http://elifesciences.org/content/3/e02869"}}
~~ [[http://elifesciences.org/content/3/e02869 Tumor evolutionary directed graphs and the history of chronic lymphocytic leukemia]]
~~ **[[http://zhangroup.aporc.org/JiguangWang Jiguang Wang#]]**, Hossein Khiabanian, Davide Rossi, Giulia Fabbri, Valter Gattei, Francesco Forconi, Luca Laurenti, Roberto Marasca, Giovanni Del Poeta, Robin Foà, Laura Pasqualucci, Gianluca Gaidano, Raul Rabadan#.
~~//eLife//, DOI:10.7554/eLife.02869, 2014. (#corresponding authors). [[http://systemsbiology.columbia.edu/news/distinguishing-patterns-of-tumor-evolution-in-chronic-lymphocytic-leukemia :::News in Columbia:::]] ---
{{image class="left" alt="srep logo" url="images/users/wjg27.png" link="http://www.nature.com/nature/journal/vaop/ncurrent/full/nature13580.html"}}
~~ [[http://www.nature.com/nature/journal/vaop/ncurrent/full/nature13580.html Noncoding RNA transcription targets AID to divergently transcribed loci in B cells]]
~~ Evangelos Pefanis*, **[[http://zhangroup.aporc.org/JiguangWang Jiguang Wang*]]**, Gerson Rothschild*, Junghyun Lim, Jaime Chao, Raul Rabadan, Aris N. Economides, Uttiya Basu
~~ //Nature//, 514(7522), 389–393, doi:10.1038/nature13580, 2014. (* co-first authors). --- [[http://f1000.com/prime/718530138 :::This paper has been evaluated by F1000:::]]
{{image class="left" alt="srep logo" url="images/users/wjg_cell2016.png" link="http://www.sciencedirect.com/science/article/pii/S009286741501692X"}}
~~ Molecular Profiling Reveals Biologically Discrete Subsets and Pathways of Progression in Diffuse Glioma.
~~ Michele Ceccarelli, Floris P Barthel, Tathiane M Malta, Thais S Sabedot, Sofie R Salama, Bradley A Murray, Olena Morozova, Yulia Newton, Amie Radenbaugh, Stefano M Pagnotta, Samreen Anjum, **[[http://zhangroup.aporc.org/JiguangWang Jiguang Wang]]**, Ganiraju Manyam, Pietro Zoppoli, Shiyun Ling, Arjun A Rao, Mia Grifford, Andrew D Cherniack, Hailei Zhang, Laila Poisson, Carlos Gilberto Carlotti, Daniela Pretti da Cunha Tirapelli, Arvind Rao, Tom Mikkelsen, Ching C Lau, WK Alfred Yung, Raul Rabadan, Jason Huse, Daniel J Brat, Norman L Lehman, Jill S Barnholtz-Sloan, Siyuan Zheng, Kenneth Hess, Ganesh Rao, Matthew Meyerson, Rameen Beroukhim, Lee Cooper, Rehan Akbani, Margaret Wrensch, David Haussler, Kenneth D Aldape, Peter W Laird, David H Gutmann, TCGA Research Network, Houtan Noushmehr, Antonio Iavarone, Roel GW Verhaak.
~~ //Cell//, Volume 164, Issue 3, 550-563, 2016.
{{image class="left" alt="srep logo" url="images/users/cr2015.png" link="http://www.cell.com/cell-reports/fulltext/S2211-1247(15)01112-2"}}
~~ Transcriptomics identify CD9 as a marker of murine IL10-competent regulatory B cells.
~~ Jianbo Sun, **[[http://zhangroup.aporc.org/JiguangWang Jiguang Wang]]**, Evangelos Pefanis, Jaime Chao, Gerson Rothschild, Isao Tachibana, Jun Kui Chen, Ivaylo I. Ivanov, Raul Rabadan, Yoshito Takeda, Uttiya Basu
~~ //Cell Reports//, Volume 13, Issue 6, p1110–1117, 10 November 2015.
{{image class="left" alt="NAR logo" url="images/users/wjg15.png" link="http://nar.oxfordjournals.org/content/39/13/e87"}}
~~ NOA: a novel Network Ontology Analysis method.
~~ **[[http://zhangroup.aporc.org/JiguangWang Jiguang Wang]]**, Qiang Huang, Zhi-Ping Liu, Yong Wang, Ling-Yun Wu, Luonan Chen, Xiang-Sun Zhang.
~~ //Nucleic Acids Research//, doi: 10.1093/nar/gkr251, 2011.
~~ [[http://www.aporc.org/noa/ ::NOA Webserver::]] [[http://f1000.com/10865956 :::This paper has been evaluated by F1000:::]]
{{image class="left" alt="PCB logo" url="images/users/wjg16.png" link="http://www.ploscompbiol.org/article/info%3Adoi%2F10.1371%2Fjournal.pcbi.1000521"}}
~~ Disease-aging network reveals significant roles of aging genes in connecting genetic diseases.
~~ **[[http://zhangroup.aporc.org/JiguangWang Jiguang Wang]]**, Shihua Zhang, Yong Wang, Luonan Chen, and Xiang-Sun Zhang.
~~ //PLoS Comput Biol//, 5(9): e1000521. doi:10.1371/journal.pcbi.1000521, 2009.---
{{image class="left" alt="srep logo" url="images/users/ot2016.png" link="http://www.ncbi.nlm.nih.gov/pubmed/26883104"}}
~~ Prognostic and therapeutic role of targetable lesions in B-lineage acute lymphoblastic leukemia without recurrent fusion genes.
~~ M Messina*, S Chiaretti*, **[[http://zhangroup.aporc.org/JiguangWang Jiguang Wang*]]**, AL Fedullo, N Peragine, V Gianfelici, A Piciocchi, F Brugnoletti, F Di Giacomo, S Pauselli, AB Holmes, MC Puzzolo, G Ceglie, V Apicella, M Mancini, G Te Kronnie, AM Testi, A Vitale, M Vignetti, A Guarini, R Rabadan, R Foà.
~~ //Oncotarget//, doi: 10.18632/oncotarget.7356, 2016. --- [[http://f1000.com/prime/726151961 :::This paper has been evaluated by F1000:::]]
{{image class="left" alt="srep logo" url="images/users/wjg_mbs2016.png" link="http://pubs.rsc.org/is/content/articlelanding/2016/mb/c5mb00782h#!divAbstract"}}
~~ Network stratification analysis for identifying function-specific network layers.
~~ C Zhang*, **[[http://zhangroup.aporc.org/JiguangWang Jiguang Wang*]]**, C Zhang, J Liu, D Xu, L Chen.
~~ //Molecular BioSystems//, 12(4):1232-40, 2016.
{{image class="left" alt="srep logo" url="images/users/BJH2015.png" link="http://onlinelibrary.wiley.com/doi/10.1111/bjh.13859/full"}}
~~ [[http://onlinelibrary.wiley.com/doi/10.1111/bjh.13859/full Inter- and intra-patient clonal and subclonal heterogeneity of chronic lymphocytic leukaemia: evidences from circulating and lymph nodal compartments]]
~~ Ilaria Del Giudice*, Marilisa Marinelli*, **[[http://zhangroup.aporc.org/JiguangWang Jiguang Wang*]]**, Silvia Bonina, Monica Messina, Sabina Chiaretti, Caterina Ilari, Luciana Cafforio, Sara Raponi, Francesca R. Mauro, Valeria Di Maio, Maria S. De Propris, Mauro Nanni, Carmela Ciardullo, Davide Rossi, Gianluca Gaidano, Anna Guarini, Raul Rabadan and Robin Foà.
~~ //British Journal of Haematology//, DOI: 10.1111/bjh.13859, 2015. (* co-first authors).
{{image class="left" alt="srep logo" url="images/users/jmcb2015.png" link="http://jmcb.oxfordjournals.org/content/7/3/203"}}
~~ An information theoretic method to identify combinations of genomic alterations that promote glioblastoma.
~~ Rachel D. Melamed, **[[http://zhangroup.aporc.org/JiguangWang Jiguang Wang]]**, Antonio Iavarone and Raul Rabadan.
~~ //J Mol Cell Biol//, doi: 10.1093/jmcb/mjv026, 2015.
{{image class="left" alt="srep logo" url="images/users/wjg29cbio.png" link="http://benthamscience.com/journals/current-bioinformatics/article/138764/"}}
~~ Network propagation reveals novel genetic features predicting drug response of cancer cell lines.
~~ **[[http://zhangroup.aporc.org/JiguangWang Jiguang Wang*]]**, Judith Kribelbauer*, Raul Rabadan.
~~ //Current Bioinformatics//, Volume 11, issue 5, 2016.
{{image class="left" alt="srep logo" url="images/users/wjg26.png" link="http://math.scichina.com:8081/sciA/CN/abstract/abstract514035.shtml"}}
~~ The research on molecular network models of complex disease (in Chinese)
~~**[[http://zhangroup.aporc.org/JiguangWang Jiguang Wang*]]**
~~ //Sci Sin Math//, 44(4): 317-328, doi: 10.1360/012013-143, 2014.
{{image class="left" alt="srep logo" url="images/users/wjg23.png" link="http://bloodjournal.hematologylibrary.org/content/early/2014/02/05/blood-2013-11-539726.short"}}
~~ Clinical impact of small TP53 mutated subclones in chronic lymphocytic leukemia
~~ D Rossi, H Khiabanian, V Spina, C Ciardullo, A Bruscaggin, R Famà, Silvia Rasi, Sara Monti, Clara Deambrogi, Lorenzo De Paoli, **[[http://zhangroup.aporc.org/JiguangWang Jiguang Wang]]**, Valter Gattei, Anna Guarini, Robin Foà, Raul Rabadan, and Gianluca Gaidano
~~ //Blood//, blood-2013-11-539726, 2014.
{{image class="left" alt="srep logo" url="images/users/wjg22.png" link="http://www.nature.com/leu/journal/vaop/ncurrent/full/leu2013384a.html"}}
~~ PU. 1 is essential for MLL leukemia partially via crosstalk with the MEIS/HOX pathway
~~ J Zhou, J Wu, B Li, D Liu, J Yu, X Yan, S Zheng, **[[http://zhangroup.aporc.org/JiguangWang J Wang]]**, L Zhang, L Zhang, F He, Q Li, A Chen, Y Zhang, X Zhao, Y Guan, X Zhao, J Yan, J Ni, M A Nobrega, B Löwenberg, R Delwel, P J M Valk, A Kumar, L Xie, D G Tenen, G Huang and Q-f Wang
~~ //Leukemia//, doi: 10.1038/leu.2013.384, 2014.
{{image class="left" alt="srep logo" url="images/users/wjg21.png" link="http://jem.rupress.org/content/210/11/2273.abstract"}}
~~ Genetic lesions associated with chronic lymphocytic leukemia transformation to Richter syndrome.
~~ Giulia Fabbri, Hossein Khiabanian, Antony B Holmes, **[[http://zhangroup.aporc.org/JiguangWang Jiguang Wang]]**, Monica Messina, Charles G Mullighan, Laura Pasqualucci, Raul Rabadan, Riccardo Dalla-Favera
~~ //Journal of Experimental Medicine//, 10/2013; DOI:10.1084/jem.20131448, 2013.
{{image class="left" alt="srep logo" url="images/users/wjg20.png" link="http://genesdev.cshlp.org/content/27/16/1821.full"}}
~~ E3-ubiquitin ligase Nedd4 determines the fate of AID-associated RNA polymerase II in B cells.
~~ Jianbo Sun, Celia D. Keim, **[[http://zhangroup.aporc.org/JiguangWang Jiguang Wang]]**, David Kazadi, Paula M. Oliver, Raul Rabadan and Uttiya Basu
~~ //Genes & Dev.//, 27: 1821-1833, 2013.
{{image class="left" alt="srep logo" url="images/users/wjg24.png" link="http://www.jimmunol.org/cgi/content/meeting_abstract/190/1_MeetingAbstracts/174.23"}}
~~ B cell development and IL-10 secretion.
~~Uttiya Basu, Jianbo Sun, and **[[http://zhangroup.aporc.org/JiguangWang Jiguang Wang]]**
~~//The Journal of Immunology//, 190, 174.23, 2013.
{{image class="left" alt="srep logo" url="images/users/wjg19.gif" link="http://bioinformatics.oxfordjournals.org/content/early/2013/07/03/bioinformatics.btt334"}}
~~ NOA: A Cytoscape Plugin for Network Ontology Analysis.
~~ Chao Zhang*, **[[http://zhangroup.aporc.org/JiguangWang Jiguang Wang*]]**, Kristina Hanspers, Dong Xu, Luonan Chen, Alexander R. Pico.
~~ //Bioinformatics//, 29 (16): 2066-2067, 2013. (* co-first authors)
~~ [[http://apps.cytoscape.org/apps/noa NOA is now available in Cytoscape!! App store and Plug-in manager]]
{{image class="left" alt="srep logo" url="images/users/wjg11.png" link="http://www.nature.com/srep/2013/130121/srep01097/full/srep01097.html"}}
~~ APG: an Active Protein-Gene Network Model to Quantify Regulatory Signals in Complex Biological Systems.
~~ **[[http://zhangroup.aporc.org/JiguangWang Jiguang Wang]]**, Yidan Sun, Si Zheng, Xiang-Sun Zhang, Hua-Rong Zhou, Luonan Chen.
~~ //Scientific Reports//, 3 : 1097, DOI: 10.1038/srep01097, 2013.
{{image class="left" alt="JMCB logo" url="images/users/wjg14.png" link="http://jmcb.oxfordjournals.org/content/4/4/197"}}
~~ Rewiring drug-activated p53-regulatory network from suppressing to promoting tumorigenesis.
~~ Wei Song*, **[[http://zhangroup.aporc.org/JiguangWang Jiguang Wang*]]**, Ying Yang, Nai-He Jing, Xiang-Sun Zhang, Luonan Chen, Jia-Rui Wu
~~ //Journal of Molecular Cell Biology // 4(3), doi: 10.1093/jmcb/mjs029, 2012 (* co-first authors).
{{image class="left" alt="Cancer Letters logo" url="images/users/wjg12.png" link="http://www.sciencedirect.com/science/article/pii/S0304383512006490#"}}
~~ Whole-exome Sequencing Reveals Recurrent Somatic Mutation Networks in Cancer.
~~ Xiaoping Liu*, **[[http://zhangroup.aporc.org/JiguangWang Jiguang Wang*]]**, Luonan Chen.
~~ //Cancer Letters//, 2012 (* co-first authors).
{{image class="left" alt="JEM logo" url="images/users/wjg13.png" link="http://jem.rupress.org/content/early/2012/08/07/jem.20120904.short"}}
~~ The coding genome of splenic marginal zone lymphoma: activation of NOTCH2 and other pathways regulating marginal zone development.
~~ Davide Rossi, Vladimir Trifonov, Marco Fangazio, Alessio Bruscaggin, Silvia Rasi, Valeria Spina, Sara Monti, Tiziana Vaisitti, Francesca Arruga, Rosella Famà, Carmela Ciardullo, Mariangela Greco, Stefania Cresta, Daniela Piranda, Antony Holmes, Giulia Fabbri, Monica Messina, Andrea Rinaldi, **[[http://zhangroup.aporc.org/JiguangWang Jiguang Wang]]**, Claudio Agostinelli, Pier Paolo Piccaluga, Marco Lucioni, Fabrizio Tabbò, Roberto Serra, Silvia Franceschetti, Clara Deambrogi, Giulia Daniele, Valter Gattei, Roberto Marasca, Fabio Facchetti, Luca Arcaini, Giorgio Inghirami, Francesco Bertoni, Stefano A Pileri, Silvia Deaglio, Robin Foà, Riccardo Dalla-Favera, Laura Pasqualucci, Raul Rabadan, Gianluca Gaidano.
~~ //The Journal of Experimental Medicine //, 209(9): 1537-1551, 2012.
{{image class="left" alt="EPL logo" url="images/users/wjg17.png" link="http://www.iop.org/EJ/abstract/0295-5075/87/3/38002"}}
~~ Modularity optimization in community detection of complex networks.
~~ Xiang-Sun Zhang, Rui-Sheng Wang, Yong Wang, **[[http://zhangroup.aporc.org/JiguangWang Jiguang Wang]]**, Yu-Qing Qiu, Lin Wang, and Luonan Chen.
~~ // Europhysics Letters//, 87: 38002, 2009.
~~ [[http://zhangroup.aporc.org/images/files/epl.pdf ::PDF download::]] [[http://iopscience.iop.org/0295-5075/page/Best%20of%202009%20Collection :::This paper is selected as EPL Best of 2009 collection:::]]
{{image class="left" alt="JSSC logo" url="images/users/wjg18.png" link="http://www.springerlink.com/content/7241802320q57g74/?p=f9a87302648f43d3b9d7c0386b86459f&pi=10"}}
~~ Remarks on network community properties
~~ **[[http://zhangroup.aporc.org/JiguangWang Jiguang Wang]]**, Yuqing Qiu, Rui-Sheng Wang, Xiang-Sun Zhang.
~~ //Jrl Syst Sci & Complexity//, 21: 637-644, 2008.
~~ [[http://zhangroup.aporc.org/images/files/2008-J-10-jssc.pdf ::PDF download::]] ---
=== {{color c="green" text="Books"}} ===
~-PhD Thesis: The Research on Molecular Network Models of Complex Disease, [[http://zhangroup.aporc.org/jiguangwangPhdThesisAbstract Abstract]]
~-Contribution to [[http://www.springer.com/new+%26+forthcoming+titles+(default)/book/978-1-4419-9862-0 Encyclopedia of Systems Biology]]: Clustering methods, Co-expression, Edge ontology, Functional enrichment analysis, Gene ontology, Ontology analysis of biological networks, Partial correlation coefficient, Pearson correlation coefficient, Time-delay correlation
----
=== {{color c="green" text="Links"}} ===
~-[[https://rabadan.c2b2.columbia.edu/cgi-bin/hgGateway EXOTOME browser]] | [[http://nrnb.org/tools/noa NOA Manual Page in NRNB]] | [[http://apps.cytoscape.org/apps/noa NOA Cytoscape Plug-in in Cytoscape App Store]] | [[http://www.aporc.org/noa/ NOA Webserver]]
~-[[http://www.c2b2.columbia.edu/rabadan/ Rabadan Lab]] | [[http://www.basulabcolumbia.org Basu Lab]] | [[http://sourcedb.big.cas.cn/yw/pl/fs/201101/t20110127_3068704.html Wang Lab]] | [[http://digbio.missouri.edu/ Xu's Digital Biology Lab]] | [[http://www.sysbio.ac.cn/cb/chenlab/index.htm Chen Lab]] | [[http://zhangroup.aporc.org/ Zhangroup]]
~-[[http://www.iscb.org/ ISCB ]] | [[http://www.bioinformatics.fr/jobs.php Bioinformatics Jobs]]
~-[[http://www.columbia.edu/ Columbia University]] | [[http://www.missouri.edu/ University of Missouri]] | [[http://english.big.cas.cn/ Beijing Institute of Genomics]] | [[http://english.amss.cas.cn/ Academy of Mathematics & Systems Science]] | [[http://english.bit.edu.cn/ Beijing Institute of Technology]] | [[http://www.czez.cn/Index.html Cangzhou secondary high school]]
~- [[http://systemsbiology.columbia.edu/news/distinguishing-patterns-of-tumor-evolution-in-chronic-lymphocytic-leukemia Distinguishing Patterns of Tumor Evolution in Chronic Lymphocytic Leukemia]]
~- [[https://www.dbmi.columbia.edu/2015/04/congratulations-to-jiguang-wang/ Jiguang Wang named Irving Institute Precision Fellow]]
~- [[http://irvinginstitute.columbia.edu/resources/pmed_fellow_ship.html Irving Institute for Clinical and Translational research]]
~- [[http://wang-lab.ust.hk/ Wang Genomic Lab @HKUST]]
::c::----
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