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Jiguang Wang in Chengdu

Dr. Jiguang Wang (王吉光)

Associate Research Scientist, Columbia Precision Medicine Fellow | Home Page at Columbia | Jiguangwang2 中文网页 | Email:

Department of Biomedical Informatics, Department of Systems Biology, Center for Computational Biology and Bioinformatics, Columbia University College of Physicians and Surgeons, 1130 St. Nicholas Ave, ICRC Bldg 8th Floor, Office 804 D, New York, NY 10032

Jiguang Wang was born in Cangxian Hebei, China. He got his Ph.D. degree from AMSS of CAS in July 2011, and now is working at Columbia University College of Physicians and Surgeons as an Associate Research Scientist.


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Training and Education

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Research Interests

Research Projects

Awards and Honors

Selected Publications

Google Citation | ResearcherID:B-2717-2012 | ResearchGate

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Network propagation reveals novel genetic features predicting drug response of cancer cell lines.
Jiguang Wang*, Judith Kribelbauer*, Raul Rabadan.
Current Bioinformatics, accepted, 2015.

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Jiguang Wang#, Hossein Khiabanian, Davide Rossi, Giulia Fabbri, Valter Gattei, Francesco Forconi, Luca Laurenti, Roberto Marasca, Giovanni Del Poeta, Robin Foà, Laura Pasqualucci, Gianluca Gaidano, Raul Rabadan#. eLife, DOI:10.7554/eLife.02869, 2014. (#corresponding authors). New! :::News in Columbia:::

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Evangelos Pefanis*, Jiguang Wang*, Gerson Rothschild*, Junghyun Lim, Jaime Chao, Raul Rabadan, Aris N. Economides, Uttiya Basu
Nature, 514(7522), 389–393, doi:10.1038/nature13580, 2014. (* co-first authors). EXOTOME browser New!
:::This paper has been evaluated by F1000:::

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The research on molecular network models of complex disease (in Chinese)
Sci Sin Math, 44(4): 317-328, doi: 10.1360/012013-143, 2014.

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Clinical impact of small TP53 mutated subclones in chronic lymphocytic leukemia
D Rossi, H Khiabanian, V Spina, C Ciardullo, A Bruscaggin, R Famà, Silvia Rasi, Sara Monti, Clara Deambrogi, Lorenzo De Paoli, Jiguang Wang, Valter Gattei, Anna Guarini, Robin Foà, Raul Rabadan, and Gianluca Gaidano
Blood, blood-2013-11-539726, 2014.

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PU. 1 is essential for MLL leukemia partially via crosstalk with the MEIS/HOX pathway
J Zhou, J Wu, B Li, D Liu, J Yu, X Yan, S Zheng, J Wang, L Zhang, L Zhang, F He, Q Li, A Chen, Y Zhang, X Zhao, Y Guan, X Zhao, J Yan, J Ni, M A Nobrega, B Löwenberg, R Delwel, P J M Valk, A Kumar, L Xie, D G Tenen, G Huang and Q-f Wang
Leukemia, doi: 10.1038/leu.2013.384, 2014.

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Genetic lesions associated with chronic lymphocytic leukemia transformation to Richter syndrome.
Giulia Fabbri, Hossein Khiabanian, Antony B Holmes, Jiguang Wang, Monica Messina, Charles G Mullighan, Laura Pasqualucci, Raul Rabadan, Riccardo Dalla-Favera
Journal of Experimental Medicine, 10/2013; DOI:10.1084/jem.20131448, 2013.

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E3-ubiquitin ligase Nedd4 determines the fate of AID-associated RNA polymerase II in B cells.
Jianbo Sun, Celia D. Keim, Jiguang Wang, David Kazadi, Paula M. Oliver, Raul Rabadan and Uttiya Basu
Genes & Dev., 27: 1821-1833, 2013.

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B cell development and IL-10 secretion.
Uttiya Basu, Jianbo Sun, and Jiguang Wang
The Journal of Immunology, 190, 174.23, 2013.

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NOA: A Cytoscape Plugin for Network Ontology Analysis.
Chao Zhang*, Jiguang Wang*, Kristina Hanspers, Dong Xu, Luonan Chen, Alexander R. Pico.
Bioinformatics, 29 (16): 2066-2067, 2013. (* co-first authors)

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APG: an Active Protein-Gene Network Model to Quantify Regulatory Signals in Complex Biological Systems.
Jiguang Wang, Yidan Sun, Si Zheng, Xiang-Sun Zhang, Hua-Rong Zhou, Luonan Chen.
Scientific Reports, 3 : 1097, DOI: 10.1038/srep01097, 2013.

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Rewiring drug-activated p53-regulatory network from suppressing to promoting tumorigenesis.
Wei Song*, Jiguang Wang*, Ying Yang, Nai-He Jing, Xiang-Sun Zhang, Luonan Chen, Jia-Rui Wu
Journal of Molecular Cell Biology 4(3), doi: 10.1093/jmcb/mjs029, 2012 (* co-first authors).

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Whole-exome Sequencing Reveals Recurrent Somatic Mutation Networks in Cancer.
Xiaoping Liu*, Jiguang Wang*, Luonan Chen.
Cancer Letters, 2012 (* co-first authors).

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The coding genome of splenic marginal zone lymphoma: activation of NOTCH2 and other pathways regulating marginal zone development.
Davide Rossi, Vladimir Trifonov, Marco Fangazio, Alessio Bruscaggin, Silvia Rasi, Valeria Spina, Sara Monti, Tiziana Vaisitti, Francesca Arruga, Rosella Famà, Carmela Ciardullo, Mariangela Greco, Stefania Cresta, Daniela Piranda, Antony Holmes, Giulia Fabbri, Monica Messina, Andrea Rinaldi, Jiguang Wang, Claudio Agostinelli, Pier Paolo Piccaluga, Marco Lucioni, Fabrizio Tabbò, Roberto Serra, Silvia Franceschetti, Clara Deambrogi, Giulia Daniele, Valter Gattei, Roberto Marasca, Fabio Facchetti, Luca Arcaini, Giorgio Inghirami, Francesco Bertoni, Stefano A Pileri, Silvia Deaglio, Robin Foà, Riccardo Dalla-Favera, Laura Pasqualucci, Raul Rabadan, Gianluca Gaidano.
The Journal of Experimental Medicine , 209(9): 1537-1551, 2012.

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NOA: a novel Network Ontology Analysis method.
Jiguang Wang, Qiang Huang, Zhi-Ping Liu, Yong Wang, Ling-Yun Wu, Luonan Chen, Xiang-Sun Zhang.
Nucleic Acids Research, doi: 10.1093/nar/gkr251, 2011.

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Disease-aging network reveals significant roles of aging genes in connecting genetic diseases.
Jiguang Wang, Shihua Zhang, Yong Wang, Luonan Chen, and Xiang-Sun Zhang.
PLoS Comput Biol, 5(9): e1000521. doi:10.1371/journal.pcbi.1000521, 2009.

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Modularity optimization in community detection of complex networks.
Xiang-Sun Zhang, Rui-Sheng Wang, Yong Wang, Jiguang Wang, Yu-Qing Qiu, Lin Wang, and Luonan Chen.
Europhysics Letters, 87: 38002, 2009.

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Remarks on network community properties
Jiguang Wang, Yuqing Qiu, Rui-Sheng Wang, Xiang-Sun Zhang.
Jrl Syst Sci & Complexity, 21: 637-644, 2008.

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