Wiki source for GuangxuJin
""<img src="images/users/ZhangroupMainpage-jgx-3.jpg" alt="GuangxuJin" style="30%;float: right; margin: 1.0%; padding: 0.5%;">""
======Guangxu Jin Ph.D.======
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=====Present Title & Affiliation=====
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Postdoc, Department of Systems Medicine and Bioengineering, The Methodist Hospital Research Institute, Weill Cornell Medical College, Houston, TX
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=====Office Address=====
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The Methodist Hospital Research Institute
6565 Fannin ST
B5-033
Houston, TX 77030
Office: +1 (713)-441-7268
Cell: +1 (281)-627-1455
----
=====Education & Training=====
----
====Degree-Granting Education====
|=||=|||
||2005.9 ~ 2008.7||[[http://www.amss.ac.cn/amss/amsscn.html Academy of Mathematics & Systems Science, CAS]], Ph.D., Operational Research||
||2002.9 ~ 2005.7||[[http://www.synu.edu.cn/synuen/p1.html Shenyang Normal University]], M.S., Operational Research||
||1998.9 ~ 2002.7||[[http://www.synu.edu.cn/synuen/p1.html Shenyang Normal University]], B.S., Applied Mathematics||
====Postgraduate Traning====
|=||=|||
||2007.12 ~ 2008.10||Exchange Student, [[http://www.methodisthealth.com/tmhri.cfm?id=39162 The Methodist Hospital Research Institute & Weill Cornell Medical College]]||
||2008.10 ~ present||Postdoctoral Fellow, [[http://http://www.methodisthealth.com/tmhri.cfm?id=39162 The Methodist Hospital Research Institute & Weill Cornell Medical College]]||
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=====Professional Memberships=====
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American Association Cancer Research
Associate Member, 2011-present
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=====Research Interests=====
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~- Off-target drug repositioning
~- ER- and Her2- targeted therapy resistance
~- Pathway-driven drug combination
~- Next generation sequencing (de-novo assembly and RNA-seq as well as whole-genome sequencing)
----
=====Selected Publications=====
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====Peer-Reviewed Original Research Articles====
~1) __Guangxu Jin__, Changhe Fu, Hong Zhao, Kemi Cui, Jenny Chang, Stephen T.C. Wong --- **[[http://cancerres.aacrjournals.org/content/72/1/33.abstract A novel method of transcriptional response analysis to facilitate drug repositioning for cancer therapy.]] **--- //Cancer Res//, 72:33-44, 2012.
~1) __Guangxu Jin__, Hong Zhao, Xiaobo Zhou, Stephen T.C. Wong --- **[[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3117391/?tool=pubmed An enhanced Petri-net model to predict synergistic effects of pairwise drug combinations from gene microarray data.]] **--- //Bioinformatics//, 27(13):i310-6, 2011.
~1) Zhao H, Cui K, Nie F, Wang L, Brandl MB, __Jin G__, Li F, Mao Y, Xue Z, Rodriguez A, et al., ---**[[http://www.springerlink.com/content/a7514m4030782g38/ The effect of mTOR inhibition alone or combined with MEK inhibitors on brain metastasis: an in vivo analysis in triple-negative breast cancer models.]]**--- //Breast Cancer Res Treat.// 2011
~1) __Jin G__, Cui K, Zhou X, Wong ST --- **[[http://ieeexplore.ieee.org/xpls/abs_all.jsp?arnumber=5230853&tag=1 Unraveling the signal-transduction networks in cancer metastasis.]] **--- //IEEE Signal Proc Mag //**26**: 129-132, 2009.
~1) __Jin G__, Zhou X, Cui K, Zhang XS, Chen L, Wong ST --- **[[http://ieeexplore.ieee.org/Xplore/login.jsp?url=http%3A%2F%2Fieeexplore.ieee.org%2Fiel5%2F4100185%2F5344672%2F05344680.pdf%3Farnumber%3D5344680&authDecision=-203 A cross-platform method for identifying candidate network biomarkers for prostate cancer.]] **--- //IET Syst Biol //**3**(6), 505-512, 2009.
~1) Wang RS, __Jin G__, Zhang XS, Chen L --- **[[http://www.biomedcentral.com/1471-2105/10/S4/S6 Modeling post-transcriptional regulation activity of small non-coding RNAs in Escherichia coli.]]**--- //BMC Bioinformatics //**10 Suppl 4**: S6, 2009.
~1) __Jin G__, Zhou X, Wang H, Zhao H, Cui K, Zhang XS, Chen L, Hazen SL, Li K, Wong ST --- **[[http://pubs.acs.org/cgi-bin/abstract.cgi/jprobs/2008/7/i09/abs/pr8002886.html The Knowledge-Integrated network biomarkers discovery for major adverse cardiac events.]]**--- //J Proteome Res //**7**(9): 4013-4021, 2008.
~1) __Jin G__, Zhang S, Zhang XS, Chen L ---**[[http://www.plosone.org/article/fetchArticle.action?articleURI=info:doi/10.1371/journal.pone.0001207 Hubs with network motifs organize modularity dynamically in the protein-protein interaction network of yeast.]]**--- //PLoS ONE //**2**(11): e1207, 2007.
~1) Zhang S, __Jin G__, Zhang XS, Chen L (2007) ---**[[http://www3.interscience.wiley.com/journal/115804878/abstract?CRETRY=1&SRETRY=0 Discovering functions and revealing mechanisms at molecular level from biological networks.]]**--- //Proteomics// **7**(16): 2856-2869, 2007.
====Book Chapters====
~1)__Jin G__, Zhou X, Wang H, Wong ST ---**[[http://www.springerlink.com/content/nv12843n3t20p766/ The challenges in blood proteomic biomarker discovery.]]**--- //Applied Bioinformatics and Biostatistics in Cancer Research//, Springer-Verlag New York Chapter **12**, 2010.
====R2D2drug database====
- [[http://r2d2drug.org/ http://r2d2drug.org/]]
Last updated: 11/30/11
======Guangxu Jin Ph.D.======
----
=====Present Title & Affiliation=====
----
Postdoc, Department of Systems Medicine and Bioengineering, The Methodist Hospital Research Institute, Weill Cornell Medical College, Houston, TX
----
=====Office Address=====
----
The Methodist Hospital Research Institute
6565 Fannin ST
B5-033
Houston, TX 77030
Office: +1 (713)-441-7268
Cell: +1 (281)-627-1455
----
=====Education & Training=====
----
====Degree-Granting Education====
|=||=|||
||2005.9 ~ 2008.7||[[http://www.amss.ac.cn/amss/amsscn.html Academy of Mathematics & Systems Science, CAS]], Ph.D., Operational Research||
||2002.9 ~ 2005.7||[[http://www.synu.edu.cn/synuen/p1.html Shenyang Normal University]], M.S., Operational Research||
||1998.9 ~ 2002.7||[[http://www.synu.edu.cn/synuen/p1.html Shenyang Normal University]], B.S., Applied Mathematics||
====Postgraduate Traning====
|=||=|||
||2007.12 ~ 2008.10||Exchange Student, [[http://www.methodisthealth.com/tmhri.cfm?id=39162 The Methodist Hospital Research Institute & Weill Cornell Medical College]]||
||2008.10 ~ present||Postdoctoral Fellow, [[http://http://www.methodisthealth.com/tmhri.cfm?id=39162 The Methodist Hospital Research Institute & Weill Cornell Medical College]]||
----
=====Professional Memberships=====
----
American Association Cancer Research
Associate Member, 2011-present
----
=====Research Interests=====
----
~- Off-target drug repositioning
~- ER- and Her2- targeted therapy resistance
~- Pathway-driven drug combination
~- Next generation sequencing (de-novo assembly and RNA-seq as well as whole-genome sequencing)
----
=====Selected Publications=====
----
====Peer-Reviewed Original Research Articles====
~1) __Guangxu Jin__, Changhe Fu, Hong Zhao, Kemi Cui, Jenny Chang, Stephen T.C. Wong --- **[[http://cancerres.aacrjournals.org/content/72/1/33.abstract A novel method of transcriptional response analysis to facilitate drug repositioning for cancer therapy.]] **--- //Cancer Res//, 72:33-44, 2012.
~1) __Guangxu Jin__, Hong Zhao, Xiaobo Zhou, Stephen T.C. Wong --- **[[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3117391/?tool=pubmed An enhanced Petri-net model to predict synergistic effects of pairwise drug combinations from gene microarray data.]] **--- //Bioinformatics//, 27(13):i310-6, 2011.
~1) Zhao H, Cui K, Nie F, Wang L, Brandl MB, __Jin G__, Li F, Mao Y, Xue Z, Rodriguez A, et al., ---**[[http://www.springerlink.com/content/a7514m4030782g38/ The effect of mTOR inhibition alone or combined with MEK inhibitors on brain metastasis: an in vivo analysis in triple-negative breast cancer models.]]**--- //Breast Cancer Res Treat.// 2011
~1) __Jin G__, Cui K, Zhou X, Wong ST --- **[[http://ieeexplore.ieee.org/xpls/abs_all.jsp?arnumber=5230853&tag=1 Unraveling the signal-transduction networks in cancer metastasis.]] **--- //IEEE Signal Proc Mag //**26**: 129-132, 2009.
~1) __Jin G__, Zhou X, Cui K, Zhang XS, Chen L, Wong ST --- **[[http://ieeexplore.ieee.org/Xplore/login.jsp?url=http%3A%2F%2Fieeexplore.ieee.org%2Fiel5%2F4100185%2F5344672%2F05344680.pdf%3Farnumber%3D5344680&authDecision=-203 A cross-platform method for identifying candidate network biomarkers for prostate cancer.]] **--- //IET Syst Biol //**3**(6), 505-512, 2009.
~1) Wang RS, __Jin G__, Zhang XS, Chen L --- **[[http://www.biomedcentral.com/1471-2105/10/S4/S6 Modeling post-transcriptional regulation activity of small non-coding RNAs in Escherichia coli.]]**--- //BMC Bioinformatics //**10 Suppl 4**: S6, 2009.
~1) __Jin G__, Zhou X, Wang H, Zhao H, Cui K, Zhang XS, Chen L, Hazen SL, Li K, Wong ST --- **[[http://pubs.acs.org/cgi-bin/abstract.cgi/jprobs/2008/7/i09/abs/pr8002886.html The Knowledge-Integrated network biomarkers discovery for major adverse cardiac events.]]**--- //J Proteome Res //**7**(9): 4013-4021, 2008.
~1) __Jin G__, Zhang S, Zhang XS, Chen L ---**[[http://www.plosone.org/article/fetchArticle.action?articleURI=info:doi/10.1371/journal.pone.0001207 Hubs with network motifs organize modularity dynamically in the protein-protein interaction network of yeast.]]**--- //PLoS ONE //**2**(11): e1207, 2007.
~1) Zhang S, __Jin G__, Zhang XS, Chen L (2007) ---**[[http://www3.interscience.wiley.com/journal/115804878/abstract?CRETRY=1&SRETRY=0 Discovering functions and revealing mechanisms at molecular level from biological networks.]]**--- //Proteomics// **7**(16): 2856-2869, 2007.
====Book Chapters====
~1)__Jin G__, Zhou X, Wang H, Wong ST ---**[[http://www.springerlink.com/content/nv12843n3t20p766/ The challenges in blood proteomic biomarker discovery.]]**--- //Applied Bioinformatics and Biostatistics in Cancer Research//, Springer-Verlag New York Chapter **12**, 2010.
====R2D2drug database====
- [[http://r2d2drug.org/ http://r2d2drug.org/]]
Last updated: 11/30/11
