Revision [5925]
This is an old revision of GuangxuJin made by GuangxuJin on 2012-06-01 02:29:15.
Guangxu Jin Ph.D.
Present Title & Affiliation
Postdoc, Department of Systems Medicine and Bioengineering, The Methodist Hospital Research Institute, Weill Cornell Medical College, Houston, TX
Office Address
The Methodist Hospital Research Institute
6565 Fannin ST
B5-033
Houston, TX 77030
Office: +1 (713)-441-7268
Cell: +1 (281)-627-1455
Education & Training
Degree-Granting Education
| 2005.9 ~ 2008.7 | Academy of Mathematics & Systems Science, CAS, Ph.D., Operational Research |
| 2002.9 ~ 2005.7 | Shenyang Normal University, M.S., Operational Research |
| 1998.9 ~ 2002.7 | Shenyang Normal University, B.S., Applied Mathematics |
Postgraduate Traning
| 2007.12 ~ 2008.10 | Exchange Student, The Methodist Hospital Research Institute & Weill Cornell Medical College |
| 2008.10 ~ present | Postdoctoral Fellow, The Methodist Hospital Research Institute & Weill Cornell Medical College |
Professional Memberships
American Association Cancer Research
Associate Member, 2011.2 - present
Intelligent Systems for Molecular Biology
Member, 2012.4 - present
American Chemical Society
Member, 2012.2 - present
Research Interests
- Pathway-driven drug repositioning
- ER- and Her2- targeted therapy resistance
- Pathway-driven drug combination
- Next generation sequencing (RNA-Seq pipelines and DNA-Seq pipelines)
Selected Publications
Peer-Reviewed Original Research Articles
- Guangxu Jin, Changhe Fu, Hong Zhao, Kemi Cui, Jenny Chang, Stephen T.C. Wong
A novel method of transcriptional response analysis to facilitate drug repositioning for cancer therapy.
Cancer Res, 72:33-44, 2012.
- Guangxu Jin, Hong Zhao, Xiaobo Zhou, Stephen T.C. Wong
An enhanced Petri-net model to predict synergistic effects of pairwise drug combinations from gene microarray data.
Bioinformatics, 27(13):i310-6, 2011.
- Zhao H, Cui K, Nie F, Wang L, Brandl MB, Jin G, Li F, Mao Y, Xue Z, Rodriguez A, et al.,
The effect of mTOR inhibition alone or combined with MEK inhibitors on brain metastasis: an in vivo analysis in triple-negative breast cancer models.
Breast Cancer Res Treat. 2011
- Jin G, Cui K, Zhou X, Wong ST
Unraveling the signal-transduction networks in cancer metastasis.
IEEE Signal Proc Mag 26: 129-132, 2009.
- Jin G, Zhou X, Cui K, Zhang XS, Chen L, Wong ST
A cross-platform method for identifying candidate network biomarkers for prostate cancer.
IET Syst Biol 3(6), 505-512, 2009.
- Wang RS, Jin G, Zhang XS, Chen L
Modeling post-transcriptional regulation activity of small non-coding RNAs in Escherichia coli.
BMC Bioinformatics 10 Suppl 4: S6, 2009.
- Jin G, Zhou X, Wang H, Zhao H, Cui K, Zhang XS, Chen L, Hazen SL, Li K, Wong ST
The Knowledge-Integrated network biomarkers discovery for major adverse cardiac events.
J Proteome Res 7(9): 4013-4021, 2008.
- Jin G, Zhang S, Zhang XS, Chen L
Hubs with network motifs organize modularity dynamically in the protein-protein interaction network of yeast.
PLoS ONE 2(11): e1207, 2007.
- Zhang S, Jin G, Zhang XS, Chen L (2007)
Discovering functions and revealing mechanisms at molecular level from biological networks.
Proteomics 7(16): 2856-2869, 2007.
Book Chapters
- Jin G, Zhou X, Wang H, Wong ST
The challenges in blood proteomic biomarker discovery.
Applied Bioinformatics and Biostatistics in Cancer Research, Springer-Verlag New York Chapter 12, 2010.
R2D2drug database
Last updated: 6/30/12
